The London Central Mosque, also known as Regent's Park Mosque, was opened on November 1977 costing £6.5 million. The Mosque was opened by King George VI. Efforts to design a mosque in central London began in the 1900s, with Lord Headley, a convert to Islam, being a key figure leading the project. Funding came from several administrations, including King Faisal of Saudi Arabia and Sultan Qaboos of the Sultanate of Oman. Construction was completed three years after the site was acquired by Churchill's War Cabinet, and gifted by the Government to British Muslims as a recognition of the importance of Islam in an increasingly multicultural society.

 The mosque was built by John Laing & Son between 1974 and 1977, and designed by Sir Frederick Gibberd, who won an international contest for the mosque's architect. Architecturally, the mosque is a presentation of traditional Islamic designs, with its beauty rooted in its simplicity. It combines architectural traditions of British modernism with historic Islamic forms, a testament to the countries intersecting British and Islamic history. The main building consists of two prayer halls, and the main hall can accommodate over 5,000 male worshippers, with women praying on a balcony overlooking the hall. It is decorated with traditional mosaics. The Mosque has a prominent golden dome, its interior decorated with traditional Islamic shapes, and a 140 ft high minaret. The Mosque consists of an education unit for children, an interfaith department and one of the largest and oldest Islamic reference libraries. It also has an Islamic bookshop and restaurant serving traditional foods.

 London Central Mosque has its own journal, Islamic Quarterly, where Muslim and non-Muslim scholars discuss topics relating to Islamic Law, culture and Arts. The journal first started in 1954 by the Islamic Cultural Centre, and continues to provide insight into Islamic history, and is widely published throughout universities and libraries.

The Mosque has been given Grade II* status, a recognition of its historical, cultural and architectural significance. This is a distinguished status as it defines London Central Mosque as having national importance, and warrants special efforts for its preservation.